MARC details
000 -LEADER |
fixed length control field |
02441nam a2200265Ia 4500 |
000 - LEADER |
fixed length control field |
04001naaa 00733uu |
001 - CONTROL NUMBER |
control field |
https://directory.doabooks.org/handle/20.500.12854/40469 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20211222133843.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
211013s9999 xx 000 0 und d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783039213559 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.3390/books978-3-03921-356-6 |
042 ## - AUTHENTICATION CODE |
Authentication code |
dc |
245 #0 - TITLE STATEMENT |
Title |
Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Name of publisher, distributor, etc. |
MDPI - Multidisciplinary Digital Publishing Institute |
Date of publication, distribution, etc. |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 electronic resource (322 p.) |
506 ## - RESTRICTIONS ON ACCESS NOTE |
Terms governing access |
Open Access |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson's , Alzheimer's , and Huntington's diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies. |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
Terms governing use and reproduction |
Creative Commons |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
advanced glycated end products |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Titorenko, Vladimir |
856 ## - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/40469">https://directory.doabooks.org/handle/20.500.12854/40469</a> |
856 ## - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/1490">https://mdpi.com/books/pdfview/book/1490</a> |
856 ## - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="www.oapen.org">www.oapen.org</a> |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
E-Book |