Chromatin and Epigenetics (Record no. 45509)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02377nam a2200277Ia 4500 |
| 000 - LEADER | |
| fixed length control field | 02747naaa 00325uu |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/67245 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211222134346.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211013s9999 xx 000 0 und d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781789844931 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.5772/intechopen.71387 |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Logie, Colin |
| 245 #0 - TITLE STATEMENT | |
| Title | Chromatin and Epigenetics |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | IntechOpen |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (294 p.) |
| 506 ## - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book Philosophie Zoologique and even more so since Darwin published his famous bottom-up theory of natural selection in The Origin of Species in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D higher-order organization and dynamics, and that on each structural level epigenetic modifications exist. The book Chromatin and Epigenetics addresses current issues in the fields of epigenetics and chromatin ranging from more theoretical overviews in the first four chapters to much more detailed methodologies and insights into diagnostics and treatments in the following chapters. The chapters illustrate in their depth and breadth that genetic information is stored on all structural and dynamical levels within the nucleus with corresponding modifications of functional relevance. Thus, only an integrative systems approach allows to understand, treat, and manipulate the holistic interplay of genotype and phenotype creating functional genomes. The book chapters therefore contribute to this general perspective, not only opening opportunities for a true universal view on genetic information but also being key for a general understanding of genomes, their function, as well as life and evolution in general. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Medical genetics |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aurelius Knoch, Tobias |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/67245">https://directory.doabooks.org/handle/20.500.12854/67245</a> |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://mts.intechopen.com/storage/books/6582/authors_book/authors_book.pdf">https://mts.intechopen.com/storage/books/6582/authors_book/authors_book.pdf</a> |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="www.oapen.org">www.oapen.org</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | E-Book |
| Withdrawn status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Not For Loan | Directory of Open Access Books | Directory of Open Access Books | 12/22/2021 | 12/22/2021 | 12/22/2021 | E-Book |