Lipid Peroxidation Research (Record no. 49195)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02302nam a2200277Ia 4500 |
| 000 - LEADER | |
| fixed length control field | 02581naaa 00301uu |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/67223 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211222135816.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211013s9999 xx 000 0 und d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781839685484 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.5772/intechopen.73713 |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mansour, Mahmoud |
| 245 #0 - TITLE STATEMENT | |
| Title | Lipid Peroxidation Research |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | IntechOpen |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (128 p.) |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Molecular biology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mansour, Mahmoud |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/67223">https://directory.doabooks.org/handle/20.500.12854/67223</a> |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://mts.intechopen.com/storage/books/6966/authors_book/authors_book.pdf">https://mts.intechopen.com/storage/books/6966/authors_book/authors_book.pdf</a> |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="www.oapen.org">www.oapen.org</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | E-Book |
| Withdrawn status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Not For Loan | Directory of Open Access Books | Directory of Open Access Books | 12/22/2021 | 12/22/2021 | 12/22/2021 | E-Book |