MARC details
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| fixed length control field |
04208nam a22005415i 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20230718140444.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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210202t20132014pl fo d z eng d |
| 019 ## - |
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| -- |
(OCoLC)1013942220 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9788376560564 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
DE-B1597 |
| Language of cataloging |
eng |
| Transcribing agency |
DE-B1597 |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QP801.H5 |
| Item number |
.S73 2013eb |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Field link and sequence number |
3p |
| Classification number |
616.97 |
| Assigning agency |
DE-101 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Stark, Holger, |
| Relator term |
author. |
| Relator code |
aut |
| -- |
http://id.loc.gov/vocabulary/relators/aut |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Histamine H4 receptor : |
| Remainder of title |
a Novel Drug Target For Immunoregulation and Inflammation / |
| Statement of responsibility, etc. |
Holger Stark. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Warsaw ; |
| -- |
Berlin : |
| Name of producer, publisher, distributor, manufacturer |
De Gruyter Open Poland, |
| Date of production, publication, distribution, manufacture, or copyright notice |
[2013] |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
©2014 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource (368 p.) |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 00 - FORMATTED CONTENTS NOTE |
|---|
| Title |
Frontmatter -- |
| -- |
Contents -- |
| -- |
Preface -- |
| -- |
Chapter 1 The histamine H4 receptor story -- |
| -- |
Chapter 2 Histamine H4 Receptor Ligands -- |
| -- |
Chapter 3 Histamine Metabolism -- |
| -- |
Chapter 4 Histamine Receptors and Inflammatory Cells -- |
| -- |
Chapter 5 Histamine in Asthmatic and Fibrotic Lung Disorders -- |
| -- |
Chapter 6 Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus -- |
| -- |
Chapter 7 Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity -- |
| -- |
Chapter 8 Histamine in Cancer -- |
| -- |
Chapter 9 Non Receptor-mediated Histamine Actions -- |
| -- |
Chapter 10 Perspectives in H4R Research and Therapeutic Exploitation -- |
| -- |
List of Figures -- |
| -- |
List of Tables -- |
| -- |
Index |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
|---|
| Terms governing access |
Open Access |
| Uniform Resource Identifier |
<a href="https://purl.org/coar/access_right/c_abf2">https://purl.org/coar/access_right/c_abf2</a> |
| Standardized terminology for access restriction |
unrestricted online access |
| Source of term |
star |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4 R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer. Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4 R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed. |
| 538 ## - SYSTEM DETAILS NOTE |
|---|
| System details note |
Mode of access: Internet via World Wide Web. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
|---|
| Terms governing use and reproduction |
This eBook is made available Open Access. Unless otherwise specified individually in the content, the work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND) license: |
| Uniform Resource Identifier |
<a href="https://creativecommons.org/licenses/by-nc-nd/3.0 ">https://creativecommons.org/licenses/by-nc-nd/3.0 </a> |
| -- |
<a href="https://www.degruyter.com/dg/page/open-access-policy">https://www.degruyter.com/dg/page/open-access-policy</a> |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
In English. |
| 588 0# - SOURCE OF DESCRIPTION NOTE |
|---|
| Source of description note |
Description based on online resource; title from PDF title page (publisher's Web site, viewed 02. Feb 2021) |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Histamine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Life Sciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Life sciences |
| General subdivision |
Molecular Biology. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Asthma. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Autoimmune Disorders. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
G protein coupled receptors. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
H4R ligands. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Inflammation. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pruritus. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
SCIENCE / Chemistry / General. |
| Source of heading or term |
bisacsh |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
G protein coupled receptors, H4R ligands, Inflammation, Autoimmune Disorders, Pruritus, Asthma, Allergy, Cancer, Drug Development, Drug Target, Clinical Candidates, Biogenic Amin. |
| 776 0# - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Qualifying information |
print |
| International Standard Book Number |
9788376560557 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://doi.org/10.2478/9788376560564">https://doi.org/10.2478/9788376560564</a> |
| Public note |
Open Access |
| -- |
0 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://www.degruyter.com/isbn/9788376560564">https://www.degruyter.com/isbn/9788376560564</a> |
| Public note |
Open Access |
| -- |
0 |
| 856 42 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
Cover |
| Uniform Resource Identifier |
<a href="https://www.degruyter.com/cover/covers/9788376560564.jpg">https://www.degruyter.com/cover/covers/9788376560564.jpg</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
E-Book |
