TY  - BOOK
AU  - Holban,Alina Maria
AU  - Grumezescu,Alexandru Mihai
TI  - Novel Molecular Approaches to Target Microbial Virulence
SN  - 9783110449501
AV  - RC112 .H655 2015
U1  - 570 23
PY  - 2015///]
CY  - Warsaw, Berlin : 
PB  - De Gruyter Open Poland, 
KW  - Bacterial diseases
KW  - Biotechnology
KW  - Infectious and parasitic diseases
KW  - Microbiology
KW  - SCIENCE / Life Sciences / Microbiology
KW  - bisacsh
KW  - antimicrobial therapy, molecular modulation, virulence, drug delivery nanoshuttles
N1  - Frontmatter --; Contents --; Preface --; 1 Introduction --; 2 Microbial Virulence --; 3 Alternative Methods for Infection Control --; 4 Increasing the Efficiency of Antimicrobial Compounds Using Nanotechnology --; 5 Conclusions and Perspectives --; Acknowledgements --; Bibliography --; List of Figures --; List of Tables --; Index
N2  - Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal-derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections
UR  - https://doi.org/10.1515/9783110449501
UR  - https://www.degruyter.com/isbn/9783110449501
UR  - https://www.degruyter.com/cover/covers/9783110449501.jpg
ER  -