TY - BOOK AU - Vale,Nuno AU - Correia,Alexandra AU - Falcão,Amílcar AU - Fortuna,Ana AU - Lobo,Andrea AU - Sandström,Anja AU - Silva,Artur M.S. AU - Pybus,Brandon S. AU - Sköld,Christian AU - Pereira,Cidália AU - Pinto,Diana C.G.A. AU - Lopes,Francisca AU - Alves,Gilberto AU - Santos,Hélder A. AU - Chambers,James J. AU - Pereira,João M.P. AU - Licinio,Julio AU - Wong,Ma-Li AU - Santos,Maria M.M. AU - João Martins,Maria AU - Lewis,Martin AU - Shahbazi,Mohammad-Ali AU - Ferreira,Mónica AU - Vale,Nuno AU - Almeida,Patrick AU - Fransson,Rebecca AU - Monteiro,Rosário AU - Moreira,Rui AU - Summavielle,Teresa TI - Biomedical Chemistry: Current Trends and Developments SN - 9783110468755 AV - RS403 .B5325 2015 PY - 2016///] CY - Warsaw, Berlin : PB - De Gruyter Open Poland, KW - Biochemistry KW - Organic chemistry KW - Pharmaceutical chemistry KW - SCIENCE / Chemistry / Organic KW - bisacsh KW - medicinal chemistry, natural products, drug design, drug discovery, translational research N1 - Frontmatter --; Contents --; Preface --; Section 1: Chemical Principles in Drug Design and Discovery --; 1.1 Functional Groups of Biomolecules and their Reactions --; 1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge --; Section 2: Chemical Basis of Drug Action and Diseases --; 2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development --; 2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression --; 2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile --; 2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems --; Section 3: Strategies to Develop New and Better Drugs --; 3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? --; 3.2 Targeting Calcium-mediated Excitotoxicity in the CNS --; 3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs --; 3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease --; 3.5 Current Trends and Developments for Nanotechnology in Cancer --; Index; Open Access N2 - Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry UR - https://doi.org/10.1515/9783110468755 UR - https://www.degruyter.com/isbn/9783110468755 UR - https://www.degruyter.com/cover/covers/9783110468755.jpg ER -