000			02219nam a2200301Ia 4500
000			05522naaa 01429uu
001			https://directory.doabooks.org/handle/20.500.12854/69028
005			20211222133713.0
008			211013s9999 xx 000 0 und d
020			_a9783039369102
024			_a10.3390/books978-3-03936-911-9
042			_adc
245		0	_aActinomycetes : The Antibiotics Producers
260			_aBasel, Switzerland _bMDPI - Multidisciplinary Digital Publishing Institute _c2020
300			_a1 electronic resource (362 p.)
520			_aBeyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibiotics, many scientists are currently investigating biosynthetic aspects of antibiotic production in actinomycetes. Since the emergence of next-generation sequencing technologies, the field of antibiotics research has experienced a remarkable revival. These bacteria have the potential to produce more antibiotics than previously thought possible. Some antibiotics are produced in standard media, while others require the presence of a specific signaling molecule in the medium. Others, however, are only produced when the native regulation of the biosynthesis gene cluster is overruled. This book covers topics in the field of antibiotic-producing actinomycetes. The following tops are addressed: - Approaches to access novel antibiotic producers for novel natural compounds - Omics and genome mining approaches for the discovery of novel natural compounds - Analyses and genetic engineering of antibiotic biosynthesis - Regulation of the secondary metabolism in actinomycetes
540			_aCreative Commons
653			_aStreptomyces
700	1		_aMast, Yvonne
700	1		_aMast, Yvonne
700	1		_aStegmann, Evi
700	1		_aStegmann, Evi
856			_uhttps://directory.doabooks.org/handle/20.500.12854/69028
856			_uhttps://mdpi.com/books/pdfview/book/2797
856			_uwww.oapen.org
942			_cE-BOOK
999			_c43854 _d43854