000			02119nam a2200265Ia 4500
000			02755naaa 00397uu
001			https://directory.doabooks.org/handle/20.500.12854/36172
005			20211222135943.0
008			211013s9999 xx 000 0 und d
024			_a10.4102/aosis.2019.BK84
042			_adc
100	1		_aHuisamen, Barbara
245		0	_aMedicinal Effects of Agathosma (Buchu) Extracts
260			_aDurbanville _bAOSIS _c2019
300			_a1 electronic resource (130 p.)
520			_aThe research results presented in this book span the quest of Cape Kingdom Nutraceuticals, Prof. Patrick Bouic and Prof. Barbara Huisamen to scientifically validate the health promoting properties of an aqueous extract of the plant Agathosma. To accomplish this, they made use of both in vitro and in vivo models to understand and underscore the anecdotal information of the benefits of this product. Cell based studies highlighted anti-inflammatory and anti-diabetic effects while animal-based studies were utilized to confirm the anti-diabetic effects whilst further elaborating on anti-obesity properties. In addition, technology aimed at small animals were used to follow blood pressure to demonstrate anti-hypertensive effects while ex vivo perfused hearts were studied to show that this extract also protected the heart against an ischaemic incident. In view of the current pandemic of obesity and non-communicable diseases, the research results presented in this book will be of special interest to the scientific community and health practitioners interested in cardiometabolic diseases and nutraceuticals as an alternative treatment option. In view of the failure of many pharmaceuticals to curb non-communicable diseases, these results are deemed of high importance
540			_aCreative Commons
653			_aAgathosma
700	1		_aBouic, Patrick J.D.
856			_uhttps://directory.doabooks.org/handle/20.500.12854/36172
856			_uhttps://library.oapen.org/bitstream/20.500.12657/37691/1/978-1-928396-82-6.pdf
856			_uwww.oapen.org
942			_cE-BOOK
999			_c49574 _d49574