Flipons (Record no. 81196)

MARC details
000 -LEADER
fixed length control field 03403namaa2200469uu 4500
001 - CONTROL NUMBER
control field doab135930
003 - CONTROL NUMBER IDENTIFIER
control field oapen
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260218110442.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr|mn|---annan
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240322s2024 xx |||||o ||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781003463535
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781003463535
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781032731087
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781032732961
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781040025000
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1201/9781003463535
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency oapen
Transcribing agency oapen
Modifying agency
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
042 ## - AUTHENTICATION CODE
Authentication code dc
245 00 - TITLE STATEMENT
Title Flipons
Remainder of title The Discovery of Z-DNA and Soft-Wired Genomes
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Taylor & Francis
Date of publication, distribution, etc. 2024
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (228 p.)
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
506 0# - RESTRICTIONS ON ACCESS NOTE
Standardized terminology for access restriction Unrestricted online access
Source of term star
520 ## - SUMMARY, ETC.
Summary, etc. Alan Herbert has played a leading part in discovering the biological roles for a high-energy form of DNA twisted to the left rather than to the right. Both Z-DNA and the Z-RNA sensing proteins are critical for protecting hosts against both viruses and cancers. The proteins also play critical roles in the programmed cell death of aging cells. Other types of flipons exist and alter the readout of transcripts from the genome, encoding genetic information by their shape rather than by their sequence. Many of these flipons are within repeat elements that were previously considered to be just genomic junk. Instead these genetic elements increase the adaptability of cells by flipping DNA conformation. By acting as digital switches, the different flipon types can alter cellular responses without any change to their sequence or any damage to DNA. These highly dynamic structures enable the rapid evolution of multicellular organisms. The junk DNA in repeats also encode peptide patches that enable the assembly of cellular machines. The intransitive logic involved enhances the chance of an individual surviving a constantly changing environment. Key Features Causes us to rethink how information is encoded in the genome Changes our understanding of how our genome evolved and how we protect ourselves against viruses and cancers while sparing normal cells Shows that high energy forms of DNA, such as left-handed DNA do exist inside the cell Accessible to those in academia and the general public, and speaks to the next generation, encouraging them to find their own path in scientific discovery The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non-Commercial-No Derivative License (CC-BY-NC-ND) 4.0 license.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
-- https://creativecommons.org/licenses/by-nc-nd/4.0/
-- cc
Uniform Resource Identifier <a href="https://creativecommons.org/licenses/by-nc-nd/4.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</a>
546 ## - LANGUAGE NOTE
Language note English
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biochemistry
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biophysics
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cellular biology (cytology)
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Endocrinology
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Life sciences: general issues
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular biology
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Organic chemistry
Source of heading or term bicssc
720 1# - ADDED ENTRY--UNCONTROLLED NAME
Name Herbert, Alan
Relator code aut
793 0# -
-- DOAB Library.
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://docs.google.com/spreadsheets/d/1yKIrdCPDAG_9c22mwoOIO2DOhtj65Wqa/edit?usp=sharing&ouid=106555315294820607512&rtpof=true&sd=true ">https://docs.google.com/spreadsheets/d/1yKIrdCPDAG_9c22mwoOIO2DOhtj65Wqa/edit?usp=sharing&ouid=106555315294820607512&rtpof=true&sd=true </a>
Link text List of Curated E-Books
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type E-Book
Holdings
Withdrawn status Damaged status Not for loan Home library Current library Date acquired Total Checkouts Date last seen Price effective from Koha item type
      Directory of Open Access Books Directory of Open Access Books 12/09/2024   12/09/2024 12/09/2024 E-Book

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